I’ve been reading a book titled Healing the Split – Integrating Spirit Into Our Understanding of the Mentally Ill by John E Nelson MD. My youngest sister is affected by a chronic and profound mental illness, likely paranoid schizophrenia based upon her expression of this challenging condition. Therefore, I want to understand this as much as possible.
So imagine my surprise at encountering the portion I will share with you in today’s blog. When I learned the identity of my dad’s father, I discovered he was a Danish immigrant, not yet a citizen though he would become one in the 1940s and he was married (not to my dad’s mother). With that discovery, I remain forever interested in anything to do with Denmark. I am fortunate as well to now have a direct link to a cousin in this family who lives in Denmark.
The Folkeregister, is a Danish registry containing detailed birth, family history, health records and circumstances of death for virtually every person in that country. Researchers used this resource in an attempt to separate the effects of genetic endowment from the tribulations of childhood.
Therefore, the researchers started their study looking at entire generations of people with mental problems, then cross-referenced their results with dozens of traits. To isolate inherited traits from environmentally induced ones, they focused on children adopted at birth and raised by families unrelated to the natural parents. They readily determined that children adopted from families of schizophrenic parents are more likely to become schizophrenic than children adopted from non-schizophrenic parents – no matter the circumstances of their upbringing.
But when researchers compared identical and fraternal twins who were separated at birth and raised in foster homes. they found the unexpected. The concordance for schizophrenia between identical twins is less than 50%. Identical twins have exactly the same genetic structure from conception. We would expect 100% concordance – if genes are the ONLY cause of schizophrenia. Clearly, genetic influence is powerful but other forces are involved. There are indications that ongoing genetic mutations create new genetic expressions of schizophrenia.
Not all psychotic ASCs (Altered States of Consciousness) reflect genetic abnormalities or primary brain disorders. What is inherited is a predisposition for idiosyncratic thinking and for developing psychotic ASCs when under stress. If genes do predispose some people to schizophrenia, what is the final trigger that pushes the person over that edge or boundary ? We know that family and social environments profoundly affect a growing brain, which changes throughout life. So the outcome of genetic predispositions to certain ASCs might be entirely different from family to family and culture to culture.
So both good news and cautionary expectations when one has this presented in their family line.