This is a very different kind of infertility and donation story but I love the happy ending. I hope you will too. The story comes courtesy of The Guardian and Kate Graham, as told to her by Amanda Gruendell.
Amanda was diagnosed with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome meaning that she had been born without a uterus. She did have functioning ovaries. “Couldn’t I have a uterus transplant?” she asked her doctor, only to be told that she’d be lucky to see the procedure developed in her lifetime.
She was also going through a rough patch. In 2006, I met a loving man who knew about my condition from the outset; we married three years later. I desperately wanted to be a mother, but our attempts at surrogacy and adoption failed. The relentless stress of infertility contributed to the end of our marriage. Her mom was also going through cancer treatments.
In 2014, she read about the world’s first successful uterus transplant in Sweden. The following year, a friend called her to tell her that a clinic in Cleveland, Ohio, was running the first American trial into the procedure. It would involve putting an embryo in the new uterus with the hope of creating a pregnancy.
Amanda brushed the idea off at first: there were only going to be 10 participants, and she knew many deserving women would be trying to join. Cleveland was also miles away from where she was living in Arizona. Then, a week later, she woke up thinking, “What do I have to lose?”
When the clinic called to give her more information, she started shaking. She knew the process would be long and unpredictable. First, an embryo would have to be created through in vitro fertilization using her eggs. Since she was single, she would have to use donor sperm. The embryos would then be frozen, while she waited for a uterus match from a deceased donor. If a suitable one was found and the operation successful, she would then have the embryo implanted.
That was when John showed up in her life. Actually he was one of her oldest friends and became her rock. By June 2017, they were engaged to be married. The delayed IVF (an infection caused a failed transplant in another trial participant) became a blessing. John and Amanda created their embryos a year later, just before their wedding.
Though her mother’s cancer had been improving, in 2019, it returned. She was slipping in and out of consciousness. Once when she woke, she told Amanda that she’d met her daughter in a dream. She said she was called Grace and looked just like Amanda.
A week later the call came: There was a match. Of course, she is grateful to the donor and her family, even as she knows what it is like to lose a loved one – her mother had died eight days later.
A month after the operation, at age 36, Amanda had her first period ever. Five months later, her embryo was implanted. When she took a pregnancy test and saw the second line, indicating a positive result, she admits that it just didn’t feel real.
In March 2021, Grace was born. When the doctor held her up, Amanda grabbed her; she couldn’t wait another second. Finally holding her daughter was more magical than she’d ever dreamed it would be.
Amanda says, “As I watch her today, all gummy smiles and blowing raspberries, I think back to that 17-year-old girl at the doctor’s office, and the devastation she felt. Now, there is joy. And that’s what the Cleveland clinic, my organ donor and her family did for me. I’ll be grateful to them all for ever.”